Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997460 | 0.98 | PTGS2 (0.41) | PTGS2HPGDNFE2L2MEN1KMT2A | |
| SCHEMBL17997456 | 0.93 | PTGS2 (0.39) | PTGS2HPGDNFE2L2MEN1KMT2A | |
| SCHEMBL17997454 | 0.92 | RAPGEF4 (0.43) | PTGS2NFE2L2MEN1KMT2ARAB9A | |
| SCHEMBL17997446 | 0.92 | MAPT (0.42) | PTGS2NFE2L2MEN1KMT2ARAB9A | |
| SCHEMBL17997452 | 0.86 | PTGS2 (0.57) | PTGS2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL17997442 | 0.85 | PTGS2 (0.56) | PTGS2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL17997449 | 0.84 | PTGS2 (0.48) | PTGS2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL17997465 | 0.83 | RAPGEF4 (0.53) | PTGS2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL17997476 | 0.83 | PTGS2 (0.49) | PTGS2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL2528716 | 0.80 | PTGS2 (0.59) | PTGS2HPGDMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |