Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13007202 | 0.96 | PTGS2 (0.51) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17997446 | 0.91 | MAPT (0.42) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17997457 | 0.90 | PTGS2 (0.50) | PTGS2MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL14079198 | 0.89 | PTGS2 (0.44) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL22893442 | 0.89 | PTGS2 (0.44) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17997452 | 0.87 | PTGS2 (0.57) | PTGS2MAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL17997465 | 0.86 | RAPGEF4 (0.53) | PTGS2MAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL13007203 | 0.86 | PTGS2 (0.53) | PTGS2MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL17997442 | 0.86 | PTGS2 (0.56) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17997464 | 0.84 | PTGS2 (0.44) | PTGS2MAPTGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |