Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600382 | 0.84 | HPGD (0.51) | LMNAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL2094230 | 0.81 | ALDH1A1 (0.65) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18600164 | 0.81 | HPGD (0.44) | LMNAALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL14263863 | 0.79 | TSHR (0.57) | LMNAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL19857150 | 0.79 | CYTH2 (0.48) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18007630 | 0.77 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30487417 | 0.77 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5149570 | 0.77 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11715963 | 0.77 | NLRP3 (0.59) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14972603 | 0.77 | PKM (0.56) | LMNAALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643294-B1 | AN IMPROVED RILPIVIRINE PROCESS | EMCURE PHARMACEUTICALS LTD (IN) | 2016-08-24 | — | — | EP | disclosed |