Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002730 | 0.91 | MAOA (0.44) | SCN9ASCN3ASCN1ASCN2ASCN10A | |
| SCHEMBL18002540 | 0.88 | MAOA (0.46) | MRGPRX4MAOAMAOBRAB9APPARG | |
| SCHEMBL18002575 | 0.86 | MAOA (0.46) | MAOAMAOBRAB9APPARGPPARD | |
| SCHEMBL18002663 | 0.85 | MAOA (0.57) | SCN9ASCN3ASCN1ASCN2ASCN10A | |
| SCHEMBL21944596 | 0.83 | MRGPRX4 (0.48) | SCN9ASCN3ASCN1ASCN2ASCN10A | |
| SCHEMBL18002358 | 0.83 | MAOA (0.53) | MRGPRX4MAOAMAOBRAB9A | |
| SCHEMBL18002508 | 0.81 | IDO1 (0.50) | MAOAMAOBPTGDR2S1PR1RAB9A | |
| SCHEMBL18002543 | 0.80 | MAOA (0.50) | MAOAMAOBRAB9APPARGPPARD | |
| SCHEMBL18002222 | 0.79 | MAOA (0.40) | SCN9AMRGPRX4MAOAMAOB | |
| SCHEMBL18002689 | 0.77 | MAOB (0.70) | MAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | SCN9A 3205/4885SCN3A 1758/4885SCN1A 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.