Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006320 | 0.90 | MRGPRX4 (0.41) | MRGPRX4CYP11B1CYP11B2FFAR1MAOB | |
| SCHEMBL18004696 | 0.89 | MRGPRX4 (0.43) | MRGPRX4CYP11B1CYP11B2MAOBCYP4F2 | |
| SCHEMBL18004691 | 0.88 | NR4A2 (0.44) | CYP11B1CYP11B2POLBMAPTMAOB | |
| SCHEMBL18004699 | 0.86 | MRGPRX4 (0.43) | MRGPRX4CYP11B1CYP11B2MAOBCYP4F2 | |
| SCHEMBL18006262 | 0.85 | ALOX5 (0.48) | MRGPRX4MAPTTDP1MAOB | |
| SCHEMBL18004433 | 0.85 | NR4A2 (0.47) | CYP11B1CYP11B2MAOBMAOA | |
| SCHEMBL18004695 | 0.85 | MRGPRX4 (0.40) | MRGPRX4CYP11B1CYP11B2FFAR1L3MBTL1 | |
| SCHEMBL18004687 | 0.85 | NR4A2 (0.45) | MRGPRX4CYP11B1FFAR1MAOBCYP4F2 | |
| SCHEMBL18006256 | 0.84 | MRGPRX4 (0.43) | MRGPRX4CYP11B1FFAR1MAOBCYP4F2 | |
| SCHEMBL18006254 | 0.84 | FFAR1 (0.45) | CYP11B1CYP11B2FFAR1MAOBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | MRGPRX4 4062/4885CYP11B1 126/4885CYP11B2 227/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | MRGPRX4 4062/4885CYP11B1 126/4885CYP11B2 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.