SCHEMBL1800533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5156459	0.90	ALDH1A1 (0.48)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1802929	0.86	KDM4E (0.45)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1802032	0.86	CHRM2 (0.52)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1801790	0.85	RIPK1 (0.48)	ALDH1A1KDM4ELMNARIPK1MEN1
	SCHEMBL1801380	0.83	ALDH1A1 (0.42)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1802733	0.83	RIPK1 (0.54)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1802555	0.82	USP2 (0.52)	ALDH1A1RIPK1TP53CYP2C9CYP2C19
	SCHEMBL1804135	0.82	RIPK1 (0.46)	ALDH1A1HTTKDM4ELMNARIPK1
	SCHEMBL1803894	0.82	RIPK1 (0.51)	ALDH1A1HTTRIPK1MEN1KMT2A
	SCHEMBL1804255	0.81	HTT (0.46)	ALDH1A1HTTKDM4ELMNARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.