Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641458 | 0.91 | XIAP (0.44) | ACECMA1OPRM1XIAPPSMB9 | |
| SCHEMBL5062693 | 0.90 | TACR1 (0.43) | ACECMA1SLC6A2OPRM1XIAP | |
| SCHEMBL366333 | 0.86 | TACR1 (0.51) | CMA1PSMB9 | |
| SCHEMBL7624015 | 0.86 | CMA1 (0.42) | ACECMA1XIAP | |
| SCHEMBL6885771 | 0.85 | TACR1 (0.44) | CMA1OPRM1XIAP | |
| SCHEMBL9011376 | 0.84 | OPRM1 (0.43) | SLC6A2OPRM1 | |
| SCHEMBL5063463 | 0.83 | OPRM1 (0.45) | OPRM1XIAPPSMB9 | |
| SCHEMBL615204 | 0.82 | TDP1 (0.41) | OPRM1ALDH1A1PSMB9 | |
| SCHEMBL847832 | 0.82 | CMA1 (0.49) | ACECMA1SLC6A2OPRM1XIAP | |
| SCHEMBL1800549 | 0.81 | ACE (0.42) | ACEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000038708-A9 | TREATMENT AND PREVENTION OF IMMUNE REJECTION REACTIONS | PHAIRSON MEDICAL INC (US) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000038708-A1 | TREATMENT AND PREVENTION OF IMMUNE REJECTION REACTIONS | PHAIRSON MEDICAL INC. (GB) | 2000-07-06 | — | — | WO | disclosed |