Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005802 | 0.86 | PARP1 (0.40) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26070491 | 0.79 | P2RX3 (0.47) | GRIN1GRIN2BSRD5A2LTA4HP2RX3 | |
| SCHEMBL17969160 | 0.77 | ERBB2 (0.55) | LTA4HERBB2NPC1SCN4ARAB9A | |
| SCHEMBL18005953 | 0.75 | ERBB2 (0.54) | LTA4HERBB2NPC1SCN4ARAB9A | |
| SCHEMBL18005809 | 0.73 | MAOB (0.49) | — | |
| SCHEMBL18006510 | 0.72 | PARP1 (0.41) | NPC1RAB9ANAAASMN1; SMN2 | |
| SCHEMBL18006513 | 0.72 | TSHR (0.47) | NPC1RAB9ANAAASMN1; SMN2 | |
| SCHEMBL1249608 | 0.70 | MEN1 (0.42) | P2RX3ERBB2NAAAMEN1KMT2A | |
| SCHEMBL18006046 | 0.70 | ERBB2 (0.45) | LTA4HERBB2NPC1SCN4ARAB9A | |
| SCHEMBL8534048 | 0.70 | GRIN1 (0.52) | GRIN1GRIN2BSRD5A2LTA4HP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | GRIN1 821/4885GRIN2B 1294/4885SRD5A2 937/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | GRIN1 821/4885GRIN2B 1294/4885SRD5A2 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.