Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009300 | 0.94 | PIK3CD (0.42) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL18009294 | 0.83 | MMP2 (0.46) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL18007434 | 0.81 | HCAR2 (0.38) | MMP2HCAR2 | |
| SCHEMBL18009297 | 0.80 | MAPT (0.40) | PIK3CDSMN1; SMN2 | |
| SCHEMBL18009292 | 0.80 | PIK3CD (0.41) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL27979463 | 0.80 | PIK3CD (0.50) | PIK3CDTSHRRECQLSMN1; SMN2CHRNA7 | |
| SCHEMBL18009283 | 0.79 | ALDH1A1 (0.40) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL18009461 | 0.78 | PIK3CD (0.40) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL18007451 | 0.76 | PIK3CD (0.39) | PIK3CDTSHRRECQLSMN1; SMN2MMP2 | |
| SCHEMBL18009337 | 0.75 | MMP2 (0.42) | MMP2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |