Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009292 | 0.91 | PIK3CD (0.41) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18009294 | 0.90 | MMP2 (0.46) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18007451 | 0.87 | PIK3CD (0.39) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18009300 | 0.85 | PIK3CD (0.42) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18009283 | 0.85 | ALDH1A1 (0.40) | PIK3CDTSHRRECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL18007448 | 0.84 | MEN1 (0.38) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18009462 | 0.82 | HPGD (0.40) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18007444 | 0.82 | TSHR (0.41) | TSHRRECQLSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18007443 | 0.81 | MMP2 (0.36) | PIK3CDTSHRRECQLSMN1; SMN2CTSK | |
| SCHEMBL18007449 | 0.81 | PIK3CD (0.36) | PIK3CDTSHRRECQLSMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |