Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009292 | 0.92 | PIK3CD (0.41) | MMP2KMT2APIK3CDTSHRRECQL | |
| SCHEMBL18009283 | 0.90 | ALDH1A1 (0.40) | MMP2KMT2AMEN1PIK3CDTSHR | |
| SCHEMBL18009300 | 0.90 | PIK3CD (0.42) | MMP2KMT2AMEN1PIK3CDTSHR | |
| SCHEMBL18009461 | 0.90 | PIK3CD (0.40) | MMP2KMT2AMEN1PIK3CDTSHR | |
| SCHEMBL18007451 | 0.88 | PIK3CD (0.39) | MMP2KMT2AMEN1PIK3CDTSHR | |
| SCHEMBL18007448 | 0.85 | MEN1 (0.38) | KMT2AMEN1PIK3CDTSHRRECQL | |
| SCHEMBL18009462 | 0.83 | HPGD (0.40) | MMP2KMT2AMEN1PIK3CDTSHR | |
| SCHEMBL18007444 | 0.83 | TSHR (0.41) | KMT2AMEN1TSHRRECQLSMN1; SMN2 | |
| SCHEMBL18009297 | 0.83 | MAPT (0.40) | KMT2AMEN1PIK3CDSMN1; SMN2ALDH1A1 | |
| SCHEMBL18009302 | 0.83 | PIK3CD (0.44) | MMP2PIK3CDTSHRRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |