Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009292 | 0.84 | PIK3CD (0.41) | KMT2ACTSKMMP2PIK3CDTSHR | |
| SCHEMBL18007443 | 0.83 | MMP2 (0.36) | KMT2ACTSKMEN1MMP2PIK3CD | |
| SCHEMBL18009294 | 0.83 | MMP2 (0.46) | KMT2ACTSKMEN1TLR2TLR1 | |
| SCHEMBL18009204 | 0.83 | MMP2 (0.37) | HPGDTACR1KMT2AATMKDM4E | |
| SCHEMBL18009461 | 0.82 | PIK3CD (0.40) | KMT2ACTSKMEN1MMP2PIK3CD | |
| SCHEMBL18009283 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1MMP2PIK3CDTSHR | |
| SCHEMBL18007440 | 0.81 | ATM (0.33) | HPGDTACR1KMT2AATMKDM4E | |
| SCHEMBL18007451 | 0.81 | PIK3CD (0.39) | KMT2ACTSKMEN1MMP2PIK3CD | |
| SCHEMBL18007448 | 0.80 | MEN1 (0.38) | HPGDKMT2ACTSKKDM4EMEN1 | |
| SCHEMBL18009300 | 0.79 | PIK3CD (0.42) | KMT2ACTSKMEN1MMP2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |