Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.58 |
| ▸ | ITGB7 | P26010 | 11/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 5/20 | 0.44 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009483 | 1.00 | ITGB1 (0.58) | ITGB1ITGA4ITGB7SLC7A5ALPI | |
| SCHEMBL20387784 | 0.86 | ITGA4 (0.53) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5163380 | 0.86 | ITGA4 (0.53) | ITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL15137423 | 0.85 | ITGA4 (0.52) | ITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5164799 | 0.85 | ITGA4 (0.52) | ITGB1ITGA4ITGB7 | |
| SCHEMBL18040325 | 0.84 | ITGB1 (0.52) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7382564 | 0.83 | ITGB1 (0.48) | ITGB1ITGA4ITGB7TYR | |
| SCHEMBL15139759 | 0.83 | ITGB1 (0.48) | ITGB1ITGA4ITGB7TYRTPH1 | |
| SCHEMBL15139761 | 0.83 | ITGB1 (0.48) | ITGB1ITGA4ITGB7TYRTPH1 | |
| SCHEMBL6237085 | 0.83 | ITGB1 (0.61) | ITGB1ITGA4ITGB7SLC7A5ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053723-B | Sulfonamide derivatives and pharmaceutical use thereof | EA制药株式会社 | 2021-09-03 | — | — | CN | disclosed |
| US-9822110-B2 | Sulfonamide derivative and pharmaceutical use thereof | EA PHARMA CO., LTD. (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20160244451-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244451-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | ITGA1, ITGB7, ITGB4 | ITGB1 5/4885ITGA4 4/4885ITGB7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.