Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 8/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983413 | 0.83 | POLB (0.53) | ALOX15ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1802847 | 0.83 | NPBWR1 (0.49) | NPBWR1ALOX15L3MBTL1MCHR1ALDH1A1 | |
| SCHEMBL23692637 | 0.77 | NPBWR1 (0.42) | NPBWR1ALOX15L3MBTL1MCHR1MAPT | |
| SCHEMBL1801455 | 0.77 | NPBWR1 (0.54) | NPBWR1ALOX15L3MBTL1MCHR1ALDH1A1 | |
| SCHEMBL17458965 | 0.76 | NPBWR1 (0.52) | NPBWR1ALOX15MCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8078489 | 0.75 | NPBWR1 (0.47) | NPBWR1PCSK9MCHR1CYP11B1CYP11B2 | |
| SCHEMBL5405380 | 0.75 | HRH4 (0.34) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14445360 | 0.75 | CNR1 (0.34) | ALOX15ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5428399 | 0.74 | UCHL1 (0.52) | NPBWR1ALOX15L3MBTL1MCHR1ALDH1A1 | |
| SCHEMBL5707080 | 0.73 | CYP1A2 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011619-B2 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2012-07-04 | — | — | EP | claimed |
| EP-1345580-B9 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2009-11-25 | — | — | EP | claimed |
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1345580-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2006-06-07 | — | — | EP | claimed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | claimed |
| EP-1011619-B1 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2005-09-14 | — | — | EP | claimed |
| EP-1345579-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | OREAL (FR) | 2005-06-29 | — | — | EP | claimed |
| WO-2005023209-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | WO | claimed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | L'OREAL (FR) | 2004-12-02 | — | — | US | claimed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2002051371-A1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | L'OREAL (FR) | 2002-07-04 | — | — | WO | claimed |
| WO-2002051373-A1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | L'OREAL (FR) | 2002-07-04 | — | — | WO | claimed |
| WO-2002051372-A2 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A AMINO PYRAZOLE AND A CELLULOSE COMPOUND | L'OREAL (FR) | 2002-07-04 | — | — | WO | claimed |
| EP-1011619-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 2000-06-28 | — | — | EP | claimed |
| WO-1999011231-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-03-11 | — | — | WO | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| EP-0728464-B1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| EP-0728464-A1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | KRT18, TUBB3, PPOX | NPBWR1 4752/4885PCSK9 4872/4885ALOX15 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.