Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010377 | 0.98 | HTR7 (0.69) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18028062 | 0.98 | HTR7 (0.69) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18010435 | 0.98 | HTR7 (0.69) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18010401 | 0.97 | HTR7 (0.64) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL13305299 | 0.83 | SIGMAR1 (0.58) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18896566 | 0.83 | HTR7 (0.50) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7259165 | 0.82 | SIGMAR1 (0.75) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18010373 | 0.82 | HTR7 (0.66) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL11230479 | 0.82 | SIGMAR1 (0.60) | HTR7SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL18010385 | 0.82 | HTR7 (1.00) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | claimed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | HTR7, HTR3A, HTR3B | HTR7 1/4885SIGMAR1 200/4885MEN1 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.