SCHEMBL18010367

SCHEMBL18010367

BrCCCCCn1c2ccccc2c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.59
MAOB P27338 10/20 0.59
ACHE P22303 3/20 0.59
FABP4 P15090 2/20 0.56
FABP5 Q01469 2/20 0.56
GRIN1 Q05586 8/20 0.56
GRIN2A Q12879 8/20 0.56
GRIN2B Q13224 8/20 0.56
HDAC1 Q13547 3/20 0.54
HDAC6 Q9UBN7 3/20 0.54
SLC6A2 P23975 1/20 0.51
SLC6A4 P31645 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473625 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL31156397 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL30576402 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL30274268 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL1472359 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL4203950 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL25354476 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL2700651 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL29433776 1.00 MAOA (0.59) MAOAMAOBACHEFABP4FABP5
SCHEMBL351619 0.98 FABP4 (0.58) MAOAMAOBACHEFABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112645971-B Method for directly preparing alkyl borate compound from alkyl halide 中国科学院兰州化学物理研究所 2021-12-24 CN claimed
US-20250185446-A1 HOLE-TRANSPORTING SELF-ORGANISED MONOLAYER FOR PEROVSKITE SOLAR CELLS HELMHOLTZ-ZENTRUM BERLIN FÜR MATERIALIEN UND ENERGIE GMBH (DE) 2025-06-05 US disclosed
WO-2024085603-A1 COMPOSITION FOR PREVENTING OR TREATING C-MYC-ASSOCIATED DISEASES THROUGH INHIBITION OF EXPRESSION OF UBIQUITIN-SPECIFIC PROTEASE 47 (USP47), AND USE THEREOF 이화여자대학교 산학협력단 2024-04-25 WO disclosed
WO-2023120963-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LUNG CANCER COMPRISING CARBAZOLE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT 한국과학기술연구원 2023-06-29 WO disclosed
CN-112645971-B Method for directly preparing alkyl borate compound from alkyl halide 中国科学院兰州化学物理研究所 2021-12-24 CN disclosed
CN-112645971-A Method for directly preparing alkyl borate compound from alkyl halide 中国科学院兰州化学物理研究所 2021-04-13 CN disclosed
US-9663464-B2 Carbazole derivatives acting on 5-HT7 receptor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-05-30 US disclosed
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR HTR7, HTR3A, HTR3B MAOA 707/4885MAOB 762/4885ACHE 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.