Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PRF1 | P14222 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18713827 | 0.95 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115351 | 0.95 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115340 | 0.95 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115315 | 0.95 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115338 | 0.95 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115375 | 0.93 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115339 | 0.93 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115360 | 0.93 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL18707156 | 0.93 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115359 | 0.93 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061759-B1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| EP-3061759-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | Idemitsu Kosan Co., Ltd (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | DBF4, NXF1, NCF1 | G6PD 1251/4885KDM4E 1878/4885ATM 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.