SCHEMBL1801238

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1802810	0.90	POLB (0.38)	POLBROCK2ALDH1A1TDP1KMT2A
	SCHEMBL1800564	0.89	POLB (0.42)	POLBROCK2ALDH1A1UGCGTDP1
	SCHEMBL1800927	0.82	ROCK2 (0.40)	POLBROCK2ALDH1A1TDP1KMT2A
	SCHEMBL3918968	0.81	GAA (0.46)	ALDH1A1CYP2C19KMT2ANPSR1CHRM2
	SCHEMBL2941591	0.80	GAA (0.46)	ALDH1A1CYP46A1
	SCHEMBL1800989	0.80	GAA (0.46)	ALDH1A1CYP46A1
	Hydrochloric Acid SCHEMBL1801317	0.79	GAA (0.45)	ALDH1A1CYP46A1
	SCHEMBL3925963	0.78	GAA (0.47)	ALDH1A1CYP2C19KMT2ANPSR1CCR5
	SCHEMBL2940213	0.78	RIPK1 (0.42)	CYP3A4CYP2C19KMT2AMAPK1NPSR1
	SCHEMBL1801114	0.78	RIPK1 (0.42)	CYP3A4CYP2C19KMT2AMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.