Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | PAM | P19021 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835054 | 0.89 | LMNA (0.47) | ADRA2AADRA1ATSHRMAPTBLM | |
| SCHEMBL16765644 | 0.89 | ADRA2A (0.36) | ADRA2AADRA1ATSHRMAPTBLM | |
| SCHEMBL9387033 | 0.87 | TSHR (0.65) | ADRA2AADRA1ATSHRMAPTBLM | |
| SCHEMBL4294657 | 0.85 | — | — | |
| SCHEMBL49969 | 0.85 | — | — | |
| SCHEMBL7787557 | 0.83 | — | — | |
| SCHEMBL8924003 | 0.83 | — | — | |
| SCHEMBL14889189 | 0.83 | — | — | |
| SCHEMBL10470529 | 0.83 | — | — | |
| SCHEMBL7696786 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124489-B1 | THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN INC (US) | 2020-07-15 | — | — | EP | disclosed |
| EP-3124489-A1 | THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | Fibrogen, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2016078-B1 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2011811-B1 | ACTIVE RAY CURABLE COMPOSITION, ACTIVE RAY CURABLE INKJET INK, IMAGE FORMING METHOD USING THE ACTIVE RAY CURABLE INKJET INK, AND INKJET RECORDING APPARATUS | KONICA MINOLTA MED & GRAPHIC (JP) | 2015-03-18 | — | — | EP | disclosed |
| US-8642675-B2 | Actinic ray curable composition, actinic ray curable ink-jet ink, image forming method and ink-jet recording apparatus utilizing said actinic ray curable ink-jet ink | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2014-02-04 | — | — | US | disclosed |
| EP-2347904-B1 | Ink set and ink-jet recording method utilizing uv-curable ink | KONICA MINOLTA MED & GRAPHIC (JP) | 2013-04-03 | — | — | EP | disclosed |
| EP-2347904-A2 | Inkset, ink-jet recording method and ink-jet recording device utilizing uv-curable ink | Konica Minolta Medical & Graphic, Inc. (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-7950795-B2 | Image forming method and ink-jet recording device utilizing photo-curable ink, and inkset, ink-jet recording method and ink-jet recording device utilizing photo-curable ink | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-7696223-B2 | [(2-bromo-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acid; modulates the stability and/or activity of hypoxia inducible factor (HIF) | FIBROGEN, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20090041945-A1 | ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20080180501-A1 | Actinic Ray Curable Composition, Actinic Ray Curable Ink, Image Forming Method Utilizing the Same, Ink-Jet Recording Apparatus and Epoxy Compound | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-31 | — | — | US | disclosed |
| US-7390840-B2 | Active ray curable composition, active ray curable ink, image forming method and inkjet recording apparatus utilizing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7360883-B2 | Active ray curable ink, image forming method and ink-jet recording apparatus | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20080055379-A1 | Image Forming Method and Ink-Jet Recording Device Utilizing Photo-Curable Ink, and Inkset, Ink-Jet Recording Method and Ink-Jet Recording Device Utilizing Photo-Curable Ink | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080004309-A1 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2008-01-03 | — | — | US | disclosed |
| US-20070254977-A1 | Actinic ray curable composition, actinic ray curable ink-jet ink, image forming method and ink-jet recording apparatus utilizing said actinic ray curable ink-jet ink | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-11-01 | — | — | US | disclosed |
| EP-1837357-A1 | ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, METHOD OF IMAGE FORMING THEREWITH, INKJET RECORDING APPARATUS AND EPOXY COMPOUND | Konica Minolta Medical & Graphic, Inc. (JP) | 2007-09-26 | — | — | EP | disclosed |
| EP-1826005-A1 | IMAGE FORMING METHOD AND INKJET RECORDING DEVICE USING PHOTO-CURING INK, AND INK SET, INKJET RECORDING METHOD AND INKJET RECORDING DEVICE USING PHOTO-CURING INK | Konica Minolta Medical & Graphic, Inc. (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-20050215657-A1 | Active ray curable composition, active ray curable ink, image forming method and inkjet recording apparatus utilizing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2005-09-29 | — | — | US | disclosed |
| US-20050190252-A1 | Active ray curable ink, image forming method and ink-jet recording apparatus | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080180501-A1 | Actinic Ray Curable Composition, Actinic Ray Curable Ink, Image Forming Method Utilizing the Same, Ink-Jet Recording Apparatus and Epoxy Compound | ROCK1, MACF1, ACTN1 | ADRA2A 2778/4885ADRA1A 2579/4885TSHR 4600/4885 |
| US-20080004309-A1 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | HIF1AN, HIF1A, EGLN2 | ADRA2A 3439/4885ADRA1A 3926/4885TSHR 1319/4885 |
| US-20090041945-A1 | ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS | RIF1, NAP1L4, NAP1L1 | ADRA2A 3412/4885ADRA1A 2935/4885TSHR 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.