Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 8/20 | 0.39 |
| ▸ | METAP2 | P50579 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380247 | 0.73 | DGAT1 (0.54) | LMNAKDM4ESMN1; SMN2POLBHTT | |
| SCHEMBL20149142 | 0.71 | KDM4E (0.41) | LMNAKDM4ESMN1; SMN2POLBHTT | |
| SCHEMBL31520280 | 0.71 | KDM4E (0.41) | LMNAKDM4ESMN1; SMN2POLBHTT | |
| SCHEMBL1827472 | 0.71 | LIPG (0.62) | LMNAKDM4EPOLBMETAP1CYP1A2 | |
| SCHEMBL30276915 | 0.71 | KDM4E (0.41) | LMNAKDM4ESMN1; SMN2POLBHTT | |
| SCHEMBL29413172 | 0.71 | LIPG (0.62) | LMNAKDM4EPOLBMETAP1CYP1A2 | |
| SCHEMBL16547523 | 0.71 | NPY5R (0.59) | NPY5RLMNAKDM4ESMN1; SMN2POLB | |
| SCHEMBL16543460 | 0.70 | NPY5R (0.54) | NPY5RLMNAKDM4ESMN1; SMN2POLB | |
| SCHEMBL23079973 | 0.70 | CCR1 (0.49) | LMNAKDM4ESMN1; SMN2POLBHTT | |
| SCHEMBL20954054 | 0.70 | KDM4E (0.39) | LMNAKDM4ESMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3484868-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20190315787-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | NPY5R 3673/4885LMNA 4536/4885KDM4E 3894/4885 |
| US-20190315787-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | NPY5R 4491/4885LMNA 4430/4885KDM4E 3846/4885 |
| US-11713332-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | NPY5R 4491/4885LMNA 4430/4885KDM4E 3846/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | NPY5R 4203/4885LMNA 4570/4885KDM4E 3864/4885 |
| US-20230322826-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | NPY5R 4491/4885LMNA 4430/4885KDM4E 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.