Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220878 | 0.85 | KCNH2 (0.53) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL13235107 | 0.82 | KMT2A (0.78) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18902237 | 0.82 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL17988255 | 0.79 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL17018746 | 0.79 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL16961628 | 0.78 | KCNH2 (0.53) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL18220901 | 0.76 | KCNH2 (0.45) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18220892 | 0.76 | KCNH2 (0.44) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL17022068 | 0.75 | KCNH2 (0.46) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18220908 | 0.72 | KCNH2 (0.43) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229869-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | FRED HUTCHINSON CANCER CENTER | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229869-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | CASP3, AIFM1, ATP6V1B1 | MEN1 2805/4885KMT2A 4652/4885ALDH1A1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.