SCHEMBL18016488

SCHEMBL18016488

C[C@]1(F)O[C@H](CO)C(O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 8/20 0.38
▸ PYGL P06737 3/20 0.36
▸ PYGM P11217 2/20 0.36
▸ OGA O60502 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ GBA1 P04062 1/20 0.32
▸ CDK1 P06493 1/20 0.32
▸ CCNB1 P14635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13787598 0.77 PYGB (0.38) PYGBPYGLPYGMOGALMNA
SCHEMBL12899851 0.77 PYGB (0.38) PYGBPYGLPYGMOGALMNA
SCHEMBL12929272 0.77 PYGB (0.38) PYGBPYGLPYGMOGALMNA
SCHEMBL12899847 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA
SCHEMBL9751326 0.76 PYGB (0.37) PYGBPYGLPYGMLMNAGBA1
SCHEMBL30843231 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA
SCHEMBL17285835 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA
SCHEMBL5971391 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA
SCHEMBL17285836 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA
SCHEMBL29776749 0.76 PYGB (0.37) PYGBPYGLPYGMOGALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237108-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237108-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF NSUN3, POLRMT, TRDMT1 PYGB 144/4885PYGL 232/4885PYGM 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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