Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362563 | 0.91 | KDM4E (0.39) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL23778641 | 0.91 | KDM4E (0.39) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL3108151 | 0.91 | PDK2 (0.36) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL11960920 | 0.90 | ABL1 (0.44) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL738679 | 0.90 | CA1 (0.37) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL738428 | 0.90 | NOTUM (0.39) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL738671 | 0.90 | PDK2 (0.36) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL1799389 | 0.89 | NPC1 (0.36) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL1468195 | 0.89 | KDM4E (0.37) | PDK2CA1CA2KDM4EF2 | |
| SCHEMBL3659569 | 0.89 | PDK2 (0.35) | PDK2CA1CA2KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382196-B1 | IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-12 | — | — | EP | disclosed |
| US-8722673-B2 | Imine compounds for combating invertebrate pests | BASF SE (DE) | 2014-05-13 | — | — | US | disclosed |
| US-8633134-B2 | Substituted amidine compounds for combating animal pests | BASF SE (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2382196-A2 | IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-2382195-A1 | SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20110263603-A1 | Imine Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110257011-A1 | Substituted Amidine Compounds for Combating Animal Pests | BASF SE (US) | 2011-10-20 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| WO-2010072602-A1 | SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010072781-A2 | IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263603-A1 | Imine Compounds for Combating Invertebrate Pests | INMT, PNMT, PIR | PDK2 1587/4885CA1 4820/4885CA2 4729/4885 |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | CYP4X1, AADAC, CYP3A7 | PDK2 625/4885CA1 4328/4885CA2 1990/4885 |
| US-20110257011-A1 | Substituted Amidine Compounds for Combating Animal Pests | C5, C3AR1, C1S | PDK2 3746/4885CA1 2108/4885CA2 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.