Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237405 | 0.82 | F2 (0.39) | HSD17B10ADRB3ADRA2BADRA2CXIAP | |
| SCHEMBL18018711 | 0.80 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL18018757 | 0.79 | KDM5A (0.36) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL12784133 | 0.79 | MEN1 (0.33) | MEN1 | |
| SCHEMBL18018708 | 0.79 | ADRB3 (0.38) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL13435865 | 0.77 | PSMB9 (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL12784569 | 0.76 | ADRB3 (0.32) | ADRB3ADRA2BADRA2C | |
| SCHEMBL11983932 | 0.75 | ADRB3 (0.38) | HSD17B10ADRB3ADRA2BADRA2CXIAP | |
| SCHEMBL12784514 | 0.75 | F2 (0.36) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12785105 | 0.75 | F2 (0.37) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127859-A1 | COMPOUNDS AS HEPATITIS C INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |