Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 12/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18018708 | 0.82 | ADRB3 (0.38) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL18018711 | 0.82 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL8237405 | 0.79 | F2 (0.39) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL18018723 | 0.79 | SMN1; SMN2 (0.39) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL12784133 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL12784569 | 0.74 | ADRB3 (0.32) | ADRB3ADRA2BADRA2C | |
| SCHEMBL18018720 | 0.73 | CTSB (0.39) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL11983932 | 0.73 | ADRB3 (0.38) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL13435751 | 0.73 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CXIAPBIRC3 | |
| SCHEMBL13435865 | 0.73 | PSMB9 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127859-A1 | COMPOUNDS AS HEPATITIS C INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |