Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 15/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006962 | 0.92 | DPP4 (0.34) | MEN1DPP4 | |
| SCHEMBL13071410 | 0.89 | ALOX15 (0.37) | MEN1DPP4 | |
| SCHEMBL8249373 | 0.86 | DPP4 (0.37) | MEN1DPP4 | |
| SCHEMBL13435865 | 0.86 | PSMB9 (0.32) | — | |
| SCHEMBL11976283 | 0.85 | CTSB (0.41) | — | |
| SCHEMBL8237929 | 0.85 | DPP4 (0.34) | DPP4 | |
| Hydrochloric Acid SCHEMBL4522873 | 0.84 | CTSB (0.41) | — | |
| Hydrochloric Acid SCHEMBL1683100 | 0.84 | CTSB (0.41) | — | |
| SCHEMBL8237322 | 0.83 | CTSB (0.34) | MEN1 | |
| SCHEMBL13071881 | 0.83 | CYP3A4 (0.37) | MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305698-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |