SCHEMBL1801879

SCHEMBL1801879

C=Cc1ccccc1C(C)NC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.41
SLC6A4 P31645 3/20 0.41
ALDH1A1 P00352 4/20 0.39
KCNH2 Q12809 1/20 0.37
CYP2D6 P10635 2/20 0.37
TSHR P16473 2/20 0.34
CHRM2 P08172 1/20 0.34
ADRA1A P35348 1/20 0.34
RGS12 O14924 1/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
THPO P40225 1/20 0.34
GNAI1 P63096 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10956121 0.82 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL1793642 0.79 TDP1 (0.45) ALDH1A1TSHRCYP3A4ALOX15ALOX12
SCHEMBL11031114 0.79 SLC6A4 (0.40) SLC6A4ALDH1A1KCNH2CYP2D6CHRM2
SCHEMBL10629895 0.79 SIGMAR1 (0.38) HTR2ASLC6A4ALDH1A1KCNH2CYP2D6
SCHEMBL11496619 0.79 HTT (0.32)
SCHEMBL56243 0.79 GABRA1 (0.44) ALDH1A1CYP2D6TSHRCYP3A4CYP2C9
SCHEMBL29364896 0.79 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4KMT2AMEN1
SCHEMBL29717597 0.79 GABRA1 (0.44) ALDH1A1CYP2D6TSHRCYP3A4CYP2C9
SCHEMBL6281523 0.79 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4KMT2AMEN1
SCHEMBL50011 0.79 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195810-B Tyre for vehicle wheels 倍耐力轮胎股份公司 2021-02-02 CN claimed
CN-110218281-A The preparation method of monodisperse polymer polyalcohol 锦湖石油化学株式会社 2019-09-10 CN claimed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US claimed
US-6765713-B2 STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT RICOH COMPANY, LTD. (JP) 2004-07-20 US claimed
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) 2003-12-18 US claimed
CN-106459504-B Rubber composition for tire and pneumatic tire 横滨橡胶株式会社 2019-05-10 CN disclosed
CN-104380190-B Recording medium, image recording structure and image recording set group 株式会社理光 2018-09-14 CN disclosed
CN-108350001-A Functionalized aminosilane functionalization's diene for elastomer polymer 盛禧奥欧洲有限责任公司 2018-07-31 CN disclosed
CN-105829370-B Rubber composition and vehicle tyre 大陆轮胎德国有限公司 2018-02-16 CN disclosed
CN-106459504-A Tire rubber composition and pneumatic tire 横滨橡胶株式会社 2017-02-22 CN disclosed
EP-2898367-B1 RECORDING MEDIUM, IMAGE RECORDING APPARATUS, AND IMAGE RECORDING SET RICOH CO LTD (JP) 2017-01-11 EP disclosed
US-9463262-B2 Cell adhesive material for biological tissue SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-11 US disclosed
EP-0098281-B1 ELECTRICALLY CONDUCTIVE COMPOSITIONS AND USE OF SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-10-14 EP disclosed
EP-0013156-B1 PARTICULATE STRUCTURE AND ELEMENT FOR ANALYSIS OR TRANSPORT OF A LIQUID AND METHOD OF MAKING SAID ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-05-22 EP disclosed
EP-0098281-A1 ELECTRICALLY CONDUCTIVE COMPOSITIONS AND USE OF SAME. EASTMAN KODAK CO (US) 1984-01-18 EP disclosed
US-4415626-A BINDER, HARDENER, TRANSPARENT MATTING AGENT, ELECTROCONDUCTIVITY AGENT, AND CHARGE CONTROL AGENT EASTMAN KODAK COMPANY (US) 1983-11-15 US disclosed
WO-1983002506-A1 ELECTRICALLY CONDUCTIVE COMPOSITIONS AND USE OF SAME EASTMAN KODAK COMPAY (US) 1983-07-21 WO disclosed
US-4381921-A LATTICE STRUCTURE CONTAINING MANY VOIDS EASTMAN KODAK COMPANY (US) 1983-05-03 US disclosed
US-4357363-A ADHESIVES EASTMAN KODAK COMPANY (US) 1982-11-02 US disclosed
US-4258001-A INCLUDING BIOLOGICAL FLUIDS EASTMAN KODAK COMPANY (US) 1981-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device NEFM, ERGIC1, VCL HTR2A 4024/4885SLC6A4 2838/4885ALDH1A1 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.