Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5227 | 0.92 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL9790 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL2229127 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL2417 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| Acetic Acid SCHEMBL7856370 | 0.89 | ALDH1A1 (0.38) | TERTALDH1A1KDM4ECHRM2CHRM1 | |
| Propionic Acid SCHEMBL8407104 | 0.89 | ALDH1A1 (0.38) | TERTALDH1A1KDM4ECHRM2CHRM1 | |
| Alcohol SCHEMBL7566185 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL626439 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL21752977 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 | |
| SCHEMBL21752846 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734965-A4 | NEW COMPOSITIONS AND METHODS FOR MAINTAINING EYELID HYGIENE | ADVANCED VISION RES INC (US) | 2008-06-11 | — | — | EP | claimed |
| US-20070231353-A1 | Compositons and methods for maintaining eyelid hygiene | ADVANCED VISION RESEARCH, INC. (US) | 2007-10-04 | — | — | US | claimed |
| EP-1734965-A1 | NEW COMPOSITIONS AND METHODS FOR MAINTAINING EYELID HYGIENE | Advanced Vision Research, Inc. (US) | 2006-12-27 | — | — | EP | claimed |
| US-20060116355-A1 | Eye care kit for treating periocular disease | VAN BREEN EDUARD T | 2006-06-01 | — | — | US | claimed |
| WO-2005097130-A1 | NEW COMPOSITIONS AND METHODS FOR MAINTAINING EYELID HYGIENE | ADVANCED VISION RESEARCH, INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-0015437-B1 | METHOD AND REAGENT FOR THE DETERMINATION OF CREATINE KINASE | Roche Diagnostics GmbH (DE) | 1981-11-25 | — | — | EP | claimed |
| US-4286057-A | QUANTITATIVE ANALYSIS OF CREATINE KINASE USING THE LUMINESCENT SYSTEM OF THE FIREFLY | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-25 | — | — | US | claimed |
| US-20210046181-A1 | MULTIVALENT PEPTIDE CONJUGATES FOR SUSTAINED INTRA-ARTICULAR TREATMENT OF JOINT INFLAMMATION | VALITOR, INC. | 2021-02-18 | — | — | US | disclosed |
| EP-3762036-A1 | MULTIVALENT PEPTIDE CONJUGATES FOR SUSTAINED INTRA-ARTICULAR TREATMENT OF JOINT INFLAMMATION | Valitor, Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019173777-A1 | MULTIVALENT PEPTIDE CONJUGATES FOR SUSTAINED INTRA-ARTICULAR TREATMENT OF JOINT INFLAMMATION | VALITOR, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| EP-2018103-B1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFECTION OR INFECTIOUS COLONIZATION OF THE EYELID, OCULAR SURFACE, SKIN OR EAR | ADVANCED VISION RES INC (US) | 2015-08-26 | — | — | EP | disclosed |
| US-8535736-B2 | Methods and compositions for the treatment of infection or infectious colonization of the eyelid, ocular surface, skin or ear | ADVANCED VISION RESEARCH, INC (US) | 2013-09-17 | — | — | US | disclosed |
| CN-101583341-B | Eyelid scrub composition | OCUSOFT INC | 2013-09-11 | — | — | CN | disclosed |
| WO-2005097130-A1 | NEW COMPOSITIONS AND METHODS FOR MAINTAINING EYELID HYGIENE | ADVANCED VISION RESEARCH, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050220742-A1 | Compositions and methods for maintaining eyelid hygiene | BREEN ED V | 2005-10-06 | — | — | US | disclosed |
| US-20050137205-A1 | Formulation for treating periocular disease | DBD DESIGN INC. | 2005-06-23 | — | — | US | disclosed |
| US-20050137205-A1 | Formulation for treating periocular disease | DBD DESIGN INC. | 2005-06-23 | — | — | US | disclosed |
| US-6448251-B1 | FATTY ACID ESTER OF HEPES FOR TOPICAL TREATMENT OF DERMATITIS | HAWKEYE-JENSEN, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6114337-A | Zwitteronic-fatty acid compounds having anti-inflammatory properties | PUGLIESE PETER T (US) | 2000-09-05 | — | — | US | disclosed |
| US-4286057-A | QUANTITATIVE ANALYSIS OF CREATINE KINASE USING THE LUMINESCENT SYSTEM OF THE FIREFLY | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210046181-A1 | MULTIVALENT PEPTIDE CONJUGATES FOR SUSTAINED INTRA-ARTICULAR TREATMENT OF JOINT INFLAMMATION | CD44, SYVN1, ICAM1 | TERT 4358/4885ALDH1A1 3797/4885KDM4E 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.