Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18024017 | 0.92 | KDM4E (0.53) | KDM4EALDH1A1GAAPOLBKEAP1 | |
| SCHEMBL503668 | 0.92 | KDM4E (0.57) | KDM4EALDH1A1GAAPOLBKEAP1 | |
| SCHEMBL525957 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1GAAPOLBKEAP1 | |
| SCHEMBL22840863 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1GAAPOLBKEAP1 | |
| SCHEMBL5293921 | 0.90 | KEAP1 (0.58) | KDM4EALDH1A1KEAP1SMN1; SMN2MAPK1 | |
| SCHEMBL4376068 | 0.89 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAPOLBKEAP1 | |
| SCHEMBL9812536 | 0.84 | SMN1; SMN2 (0.56) | KDM4EALDH1A1KEAP1SMN1; SMN2MAPK1 | |
| SCHEMBL12371264 | 0.82 | HRH3 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1HRH3 | |
| SCHEMBL111438 | 0.81 | TSHR (0.58) | KDM4EALDH1A1KEAP1SMN1; SMN2MAPK1 | |
| SCHEMBL10928264 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1KEAP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130968-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | YALE UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |