SCHEMBL525957

SCHEMBL525957

OCCOCCOCCN1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
POLB P06746 2/20 0.54
GAA P10253 1/20 0.54
TSHR P16473 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
KEAP1 Q14145 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HTR1A P08908 1/20 0.43
HPGD P15428 1/20 0.42
DUSP3 P51452 1/20 0.42
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22840863 1.00 KDM4E (0.55) KDM4EALDH1A1POLBGAATSHR
SCHEMBL503668 0.98 KDM4E (0.57) KDM4EALDH1A1POLBGAATSHR
SCHEMBL18024033 0.90 KDM4E (0.53) KDM4EALDH1A1POLBGAATSHR
SCHEMBL7106263 0.89 TSHR (0.61) KDM4EALDH1A1POLBTSHRL3MBTL1
SCHEMBL111438 0.87 TSHR (0.58) KDM4EALDH1A1TSHRSMN1; SMN2KEAP1
SCHEMBL4376068 0.86 ALDH1A1 (0.53) KDM4EALDH1A1POLBGAATSHR
SCHEMBL31305372 0.85 MEN1 (0.55) KDM4EALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL31305373 0.85 MEN1 (0.55) KDM4EALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL20118622 0.83 KDM4E (0.54) KDM4EALDH1A1POLBGAATSHR
SCHEMBL8966405 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362332-A Binary phthalocyanine with I-type photosensitive reaction and photo-thermal synergistic effect and preparation and application thereof 福州大学 2024-01-09 CN claimed
CN-121577501-A Polypeptide aggregation trend prediction method based on dynamic light scattering 中肽生化有限公司 2026-02-27 CN disclosed
CN-117362332-A Binary phthalocyanine with I-type photosensitive reaction and photo-thermal synergistic effect and preparation and application thereof 福州大学 2024-01-09 CN disclosed
EP-2981535-B1 UREA DERIVATIVES USEFUL AS KINASE INHIBITORS TOPIVERT PHARMA LTD (GB) 2020-12-16 EP disclosed
US-10435361-B2 Kinase inhibitors TOPIVERT PHARMA LIMITED (GB) 2019-10-08 US disclosed
EP-3111940-B1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO LTD (CN) 2018-03-21 EP disclosed
US-20180044288-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2018-02-15 US disclosed
US-9890181-B2 Silicon phthalocyanine complex, preparation method and medicinal application thereof SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO., LTD. (CN) 2018-02-13 US disclosed
US-9790174-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-10-17 US disclosed
US-9732063-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-08-15 US disclosed
US-9056914-B2 Anticancer derivatives, preparation thereof and therapeutic use thereof SANOFI (FR) 2015-06-16 US disclosed
WO-2014162126-A1 UREA DERIVATIVES USEFUL AS KINASE INHIBITORS RESPIVERT LIMITED (GB) 2014-10-09 WO disclosed
US-20140296208-A1 KINASE INHIBITORS TOPIVERT PHARMA LIMITED (GB) 2014-10-02 US disclosed
WO-2014076484-A1 KINASE INHIBITORS RESPIVERT LIMITED (GB) 2014-05-22 WO disclosed
EP-2598507-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-06-05 EP disclosed
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-05-30 US disclosed
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-05-30 US disclosed
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-05-30 US disclosed
WO-2012014147-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-02-02 WO disclosed
WO-2012014147-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044288-A1 KINASE INHIBITORS SYK, LYN, BTK KDM4E 1018/4885ALDH1A1 4408/4885POLB 3321/4885
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF MCL1, TP53, MYC KDM4E 2894/4885ALDH1A1 339/4885POLB 1182/4885
US-10435361-B2 Kinase inhibitors SYK, LYN, BTK KDM4E 1018/4885ALDH1A1 4408/4885POLB 3321/4885
US-20140296208-A1 KINASE INHIBITORS SYK, LYN, BTK KDM4E 1018/4885ALDH1A1 4408/4885POLB 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.