Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16762036 | 0.96 | CCR2 (0.37) | CCR2TRPM2PPIDKDM4EMEN1 | |
| SCHEMBL16839110 | 0.94 | CCR2 (0.36) | CCR2TRPM2PPIDKDM4EMEN1 | |
| SCHEMBL16839930 | 0.91 | LIPE (0.33) | PPIDPOLBNPSR1CETPLTB4R2 | |
| SCHEMBL16761886 | 0.73 | TSHR (0.41) | MMP13 | |
| SCHEMBL18025455 | 0.73 | CD274 (0.39) | CCR2MAPTCD274MMP1MMP2 | |
| SCHEMBL16268713 | 0.71 | GAA (0.39) | MAPTKMT2APOLBNPSR1 | |
| SCHEMBL16839659 | 0.71 | KCNQ2 (0.41) | PPIDKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL16839822 | 0.69 | MMP2 (0.41) | MAPTMMP1MMP2MMP3MMP9 | |
| SCHEMBL20197027 | 0.69 | KDM4E (0.37) | CCR2KDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL16839843 | 0.68 | PPID (0.45) | TRPM2PPIDKDM4EMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422240-B2 | Partially saturated nitrogen-containing heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2016-08-23 | — | — | US | disclosed |