Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839659 | 0.79 | KCNQ2 (0.41) | KDM4ENPSR1POLBMEN1HSP90AA1 | |
| SCHEMBL16839733 | 0.75 | KCNQ2 (0.43) | KDM4ENPSR1POLBALDH1A1MMP2 | |
| SCHEMBL16762036 | 0.70 | CCR2 (0.37) | KDM4ENPSR1POLBALDH1A1CCR2 | |
| SCHEMBL18025451 | 0.69 | CCR2 (0.36) | KDM4ENPSR1POLBCCR2MEN1 | |
| SCHEMBL16839110 | 0.69 | CCR2 (0.36) | KDM4ENPSR1POLBALDH1A1CCR2 | |
| SCHEMBL16112014 | 0.68 | LMNA (0.56) | KDM4ENPSR1POLBALDH1A1MEN1 | |
| SCHEMBL1464315 | 0.67 | MMP13 (0.59) | NPSR1ALDH1A1MEN1KMT2AMMP2 | |
| SCHEMBL24529777 | 0.66 | OPRM1 (0.46) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16839837 | 0.66 | KCNQ2 (0.47) | KDM4ENPSR1POLBALDH1A1 | |
| SCHEMBL16839111 | 0.66 | KDM4E (0.38) | KDM4EALDH1A1CCR2MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |