Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.37 |
| ▸ | GNG2 | P59768 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804613 | 0.93 | MAPT (0.55) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL13370364 | 0.81 | PTPRC (0.37) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL28192588 | 0.80 | MAPT (0.55) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL13370281 | 0.76 | MEN1 (0.45) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL1802604 | 0.76 | NPC1 (0.55) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL8551952 | 0.75 | NPC1 (0.56) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL28369522 | 0.75 | MAPT (0.46) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL1800594 | 0.73 | LMNA (0.50) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL1800373 | 0.72 | MAPT (0.63) | LMNAMAPK1MAPTMEN1NPC1 | |
| SCHEMBL873640 | 0.72 | MEN1 (0.47) | LMNAMEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330161-B1 | DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS | MENICON CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-8927618-B2 | Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens | MENICON CO., LTD. (JP) | 2015-01-06 | — | — | US | disclosed |
| EP-2330161-A1 | Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens | Menicon Co., Ltd. (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-20110116034-A1 | Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens | MENICON CO., LTD. (JP) | 2011-05-19 | — | — | US | disclosed |