Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761700 | 0.88 | MAPT (0.47) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL11575989 | 0.83 | P2RY12 (0.46) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL1802604 | 0.80 | NPC1 (0.55) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL1800594 | 0.80 | LMNA (0.50) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL3975751 | 0.80 | P2RY4 (0.62) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL11606520 | 0.79 | P2RY12 (0.60) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL8551947 | 0.78 | P2RY4 (0.44) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL375688 | 0.78 | LMNA (0.87) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL13135365 | 0.78 | NPC1 (0.65) | NPC1LMNAMAPK1RAB9ATDP1 | |
| SCHEMBL11605977 | 0.77 | P2RY12 (0.57) | NPC1LMNAMAPK1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625552-B1 | Water-reducible dye compositions | MORTON INT INC (US) | 1999-01-07 | — | — | EP | disclosed |