SCHEMBL1802604

SCHEMBL1802604

C=CCOCCc1ccc(Nc2ccc(Nc3ccc(CCOCC=C)cc3)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ LMNA P02545 2/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ MEN1 O00255 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ MTOR P42345 1/20 0.42
▸ SIRT2 Q8IXJ6 1/20 0.42
▸ PRKCA P17252 1/20 0.39
▸ P2RY4 P51582 4/20 0.39
▸ P2RY12 Q9H244 4/20 0.39
▸ CYP1A2 P05177 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804615 0.93 MEN1 (0.67) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL13370366 0.81 P2RY2 (0.39) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL1800373 0.81 MAPT (0.63) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL30887233 0.81 NPC1 (0.56) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL261844 0.81 NPC1 (0.56) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL8551952 0.80 NPC1 (0.56) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL13473966 0.78 MAPT (0.71) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL13135365 0.76 NPC1 (0.65) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL375688 0.76 LMNA (0.87) NPC1RAB9ALMNAMAPK1MEN1
SCHEMBL13370280 0.76 MEN1 (0.47) NPC1RAB9ALMNAMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3412689-B1 HYDROGENATED BLOCK-COPOLYMER HAVING ACID ANHYDRIDE GROUP AND USE THEREOF ZEON CORP (JP) 2020-10-14 — — EP disclosed
US-20190203035-A1 BLOCK-COPOLYMER HYDRIDE HAVING ACID ANHYDRIDE GROUP AND USE THEREOF ZEON CORPORATION (JP) 2019-07-04 — — US disclosed
EP-3412689-A1 BLOCK-COPOLYMER HYDRIDE HAVING ACID ANHYDRIDE GROUP AND USE THEREOF Zeon Corporation (JP) 2018-12-12 — — EP disclosed
US-20180086029-A1 RESIN COMPOSITION AND USE OF SAME ZEON CORPORATION (JP) 2018-03-29 — — US disclosed
EP-3281981-A1 RESIN COMPOSITION AND USE OF SAME Zeon Corporation (JP) 2018-02-14 — — EP disclosed
EP-2330161-B1 DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS MENICON CO LTD (JP) 2017-01-25 — — EP disclosed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 — — US disclosed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 — — US disclosed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 — — US disclosed
EP-2514791-A1 ANTHRAQUINONE PIGMENT, OCULAR LENS MATERIAL USING SAME, OCULAR LENS MATERIAL MANUFACTURING METHOD, AND OCULAR LENS Menicon Co., Ltd. (JP) 2012-10-24 — — EP disclosed
EP-2514791-A1 ANTHRAQUINONE PIGMENT, OCULAR LENS MATERIAL USING SAME, OCULAR LENS MATERIAL MANUFACTURING METHOD, AND OCULAR LENS Menicon Co., Ltd. (JP) 2012-10-24 — — EP disclosed
EP-2330161-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens Menicon Co., Ltd. (JP) 2011-06-08 — — EP disclosed
EP-2330161-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens Menicon Co., Ltd. (JP) 2011-06-08 — — EP disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 — — US disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 — — US disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 — — US disclosed
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