SCHEMBL261844

SCHEMBL261844

C=C(C)COCCc1ccc(Nc2ccc(Nc3ccc(CCOCC(=C)C)cc3)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ MAPK1 P28482 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MTOR P42345 1/20 0.43
▸ SIRT2 Q8IXJ6 1/20 0.43
▸ PRKCA P17252 1/20 0.40
▸ P2RY4 P51582 5/20 0.40
▸ CYP1A2 P05177 2/20 0.39
▸ TSHR P16473 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ PABPC1 P11940 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8032777 0.92 MAPT (0.47) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL8032990 0.92 NPC1 (0.48) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL29462117 0.83 MAPT (0.55) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL261845 0.83 MAPT (0.55) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL1802604 0.81 NPC1 (0.55) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL13473966 0.81 MAPT (0.71) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL21315445 0.79 MEN1 (0.54) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL28312216 0.79 NPC1 (0.58) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL20274482 0.78 NPC1 (0.50) NPC1RAB9ALMNAMAPK1MAPT
SCHEMBL13178023 0.78 MAPT (0.64) NPC1RAB9ALMNAMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 — — US claimed
EP-4519721-B1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INT LTD (GB) 2025-10-01 — — EP claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US claimed
US-11372267-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2022-06-28 — — US claimed
US-20200150460-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2020-05-14 — — US claimed
US-10578889-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2020-03-03 — — US claimed
US-20190317339-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2019-10-17 — — US claimed
US-10371966-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2019-08-06 — — US claimed
US-20170227790-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2017-08-10 — — US claimed
EP-0396376-B1 Polymerizable dye BAUSCH & LOMB (US) 1994-12-28 — — EP claimed
US-4997897-A Unsaturated esters or amides of aminoanthraquinone dyes BAUSCH & LOMB INCORPORATED (US) 1991-03-05 — — US claimed
JP-3072576-A — — None — — JP disclosed
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2026-05-28 — — US disclosed
US-12631791-B2 Multifunctional crosslinking agents and ophthalmic devices formed therefrom BAUSCH + LOMB IRELAND LIMITED (IE) 2026-05-19 — — US disclosed
US-20260109119-A1 STABILIZED FORMULATIONS FOR CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2026-04-23 — — US disclosed
US-6364934-B1 IMPROVING OPTICAL QUALITY IN CONTACT LENSES BY FILTERING THE HYDROPHILIC AND HYDROPHOBIC MONOMERS THEREBY FINELY DISPERSING THEM AND ANY DISSOLVED GASES BAUSCH & LOMB INCORPORATED 2002-04-02 — — US disclosed
US-6359024-B2 PHOTOPOLYMERIZATION; USING LIGHT SOURCE BAUSCH & LOMB INCORPORATED 2002-03-19 — — US disclosed
US-20010014704-A1 METHOD FOR POLYMERIZING CONTACT LENSES SOLTA MEDICAL IRELAND LIMITED (IE) 2001-08-16 — — US disclosed
JP-H0372576-A POLYMERIZABLE DYE BAUSCH & LOMB INC 1991-03-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L NPC1 3998/4885RAB9A 4835/4885LMNA 2948/4885
US-12631791-B2 Multifunctional crosslinking agents and ophthalmic devices formed therefrom ILK, MACF1, RAD51 NPC1 4753/4885RAB9A 1697/4885LMNA 301/4885
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES EPCAM, STIM1, SMCHD1 NPC1 1618/4885RAB9A 1823/4885LMNA 2741/4885
US-20260109119-A1 STABILIZED FORMULATIONS FOR CONTACT LENSES POT1, TELO2, TST NPC1 4567/4885RAB9A 4274/4885LMNA 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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