Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18026503 | 0.89 | MAOA (0.49) | MAOAMAOBARACHEKDM4E | |
| SCHEMBL12617766 | 0.88 | CYP1A1 (0.60) | CYP1A1CYP2D6CYP2B6CYP2C19CYP3A43 | |
| SCHEMBL26195635 | 0.78 | AR (0.58) | MAOAMAOBARCA12CA1 | |
| SCHEMBL18026501 | 0.76 | MAOB (0.37) | MAOAMAOBARBCHEACHE | |
| SCHEMBL16471370 | 0.74 | CA9 (0.56) | CYP1A1CYP2D6CYP2B6CYP2C19CYP3A43 | |
| SCHEMBL21724418 | 0.74 | CA12 (0.56) | CYP1A1CYP2D6CYP2B6CYP2C19CYP3A43 | |
| SCHEMBL4446592 | 0.73 | AGER (0.60) | CYP1A1CYP2D6CYP2B6CYP2C19CYP3A43 | |
| SCHEMBL2803970 | 0.73 | KMT2A (0.59) | ARCA12CA1CA9KDM4E | |
| SCHEMBL7915768 | 0.72 | ALDH1A1 (0.58) | MAOAMAOBARKDM4EALDH1A1 | |
| SCHEMBL9612697 | 0.71 | KDM4E (0.72) | CYP1A1CYP2D6CYP2B6CYP2C19CYP3A43 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243047-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243047-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | MSN, CD44, EPHA2 | CYP1A1 2585/4885CYP2D6 1358/4885CYP2B6 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.