Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18026725 | 0.83 | POLB (0.48) | HDAC4HDAC7HDAC5OPRM1OPRK1 | |
| SCHEMBL4541577 | 0.79 | HDAC4 (0.79) | HDAC4HDAC7HDAC5KMT2AHTT | |
| SCHEMBL3816046 | 0.77 | OPRM1 (0.41) | OPRM1OPRK1HTTMTNR1AMTNR1B | |
| Cyheptamide SCHEMBL29400142 | 0.74 | ALDH1A1 (0.62) | HDAC4HDAC7HDAC5HTTACP3 | |
| Cyheptamide SCHEMBL667894 | 0.74 | ALDH1A1 (0.62) | HDAC4HDAC7HDAC5HTTACP3 | |
| SCHEMBL7171729 | 0.74 | ACP3 (0.50) | HDAC4HDAC7HDAC5KMT2AHTT | |
| SCHEMBL8672028 | 0.74 | TP53 (0.48) | OPRM1MTNR1AMTNR1B | |
| SCHEMBL16559337 | 0.73 | HDAC4 (0.44) | HDAC4HDAC7HDAC5OPRM1OPRK1 | |
| SCHEMBL4163569 | 0.73 | TSHR (0.44) | OPRM1OPRK1MTNR1A | |
| SCHEMBL3879203 | 0.72 | TSHR (0.53) | HDAC4HDAC7HDAC5OPRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | HDAC4 804/4885HDAC7 655/4885HDAC5 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.