SCHEMBL1803002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1806773	0.86	AVPR1A (0.52)	TACR1FAAHALDH1A1
	SCHEMBL1802856	0.85	USP2 (0.54)	CYP2C19CYP2C9TACR1USP2CYP2D6
	SCHEMBL1800737	0.81	CYP3A4 (0.41)	CYP2C19CYP2C9FAAHCHRM3USP2
	SCHEMBL1802929	0.79	KDM4E (0.45)	CYP2C19CYP2C9HTR2BMAPK14TACR1
	SCHEMBL1800539	0.77	ALDH1A1 (0.45)	CYP2C9L3MBTL1USP2CYP2D6CYP3A4
	SCHEMBL1798378	0.77	FAAH (0.40)	TACR1FAAHCHRM3
	SCHEMBL1800466	0.75	ALDH1A1 (0.49)	CYP2C19L3MBTL1USP2CYP2D6CYP3A4
	SCHEMBL1801500	0.74	TACR1 (0.42)	CYP2C19CYP2C9HTR2BMAPK14TACR1
	SCHEMBL3917731	0.73	ALDH1A1 (0.39)	CYP2C19CYP2C9TACR1FAAHCHRM3
	SCHEMBL5151460	0.72	CHRM3 (0.39)	FAAHCHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.