Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18031026 | 0.99 | GPR3 (0.44) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL17034461 | 0.96 | L3MBTL1 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL18055719 | 0.94 | L3MBTL1 (0.41) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL18030981 | 0.93 | GPR3 (0.44) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL17034395 | 0.92 | GPR3 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL18031027 | 0.92 | GPR3 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL17034462 | 0.92 | GPR3 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL18031009 | 0.92 | GPR3 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL18031004 | 0.92 | GPR3 (0.43) | GPR3L3MBTL1KMT2AMEN1TLR9 | |
| SCHEMBL17032695 | 0.89 | GPR3 (0.57) | GPR3L3MBTL1KMT2AMEN1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061759-B1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | DBF4, DDT, SLC43A3 | GPR3 4658/4885L3MBTL1 2157/4885KMT2A 3930/4885 |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | DBF4, NXF1, NCF1 | GPR3 4779/4885L3MBTL1 2762/4885KMT2A 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.