SCHEMBL1803193

SCHEMBL1803193

CCCCCCCC1COCCO1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
EPHX1 P07099 1/20 0.64
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM3 P20309 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
THRB P10828 1/20 0.43
CYP1A2 P05177 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
SPHK1 Q9NYA1 7/20 0.40
SPHK2 Q9NRA0 6/20 0.40
PRKD3 O94806 2/20 0.36
PRKCG P05129 2/20 0.36
PRKCB P05771 2/20 0.36
PRKCA P17252 2/20 0.36
PRKCH P24723 2/20 0.36
PRKCI P41743 2/20 0.36
PRKCE Q02156 2/20 0.36
PRKCQ Q04759 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11611467 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL11615684 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL1463562 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL28284618 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL11694128 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL28042954 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL4618624 1.00 ALDH1A1 (0.69) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL18092763 0.98 ALDH1A1 (0.67) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL15301129 0.98 ALDH1A1 (0.67) ALDH1A1EPHX1CHRM2CHRM4CHRM5
SCHEMBL2811229 0.98 ALDH1A1 (0.67) ALDH1A1EPHX1CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167938-B Novel amino-imidazopyridine derivatives as Janus kinase inhibitors and medical uses thereof 阿基利昂有限公司 2024-06-14 CN disclosed
EP-4029854-A1 CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR Fibrogen, Inc. (US) 2022-07-20 EP disclosed
EP-3470397-B1 CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR FIBROGEN INC (US) 2021-12-29 EP disclosed
CN-112028020-B Process for recovering iodine from iodine bromide-containing medical organic waste liquid 山东博苑医药化学股份有限公司 2021-06-22 CN disclosed
US-10981942-B2 Crystalline form of benzylbenzene SGLT2 inhibitor THERACOS SUB, LLC (US) 2021-04-20 US disclosed
CN-112028020-A Process for recovering iodine from iodine bromide-containing medical organic waste liquid 山东博苑医药化学股份有限公司 2020-12-04 CN disclosed
EP-3568396-B1 NOVEL AMINO-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF LEO PHARMA AS (DK) 2020-11-11 EP disclosed
US-20200239510-A1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR THERACOSBIO, LLC 2020-07-30 US disclosed
US-10703751-B2 Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof LEO PHARMA A/S (DK) 2020-07-07 US disclosed
US-20200115344-A1 CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR FIBROGEN INC (US) 2020-04-16 US disclosed
US-20090187040-A1 FENOFIBRIC ACID POLYMORPHS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY, INC., A PENNSYLVANIA CORPORATION 2009-07-23 US disclosed
WO-2009091967-A2 FENOFIBRIC ACID POLYMORPHS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY (US) 2009-07-23 WO disclosed
CN-101291921-A Spiro [3.3] heptyl-dioxan derivatives and their use in liquid crystal media MERCK PATENT GMBH (DE) 2008-10-22 CN disclosed
EP-1878075-A2 ELECTRODE MATERIAL INCLUDING A LITHIUM/TRANSITION METAL COMPLEX OXIDE Phostech Lithium Inc. (CA) 2008-01-16 EP disclosed
WO-2006120332-A2 ELECTRODE MATERIAL INCLUDING A LITHIUM/TRANSITION METAL COMPLEX OXIDE PHOSTECH LITHIUM INC. (CA) 2006-11-16 WO disclosed
US-5712270-A TREATING PARKINSON*S DISEASE, DOWN*S SYNDROME, AND ALZHEIMER*S DISEASE WITH COGNITION ACTIVATORS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-01-27 US disclosed
US-5510478-A TREATMENT OF NEUROLOGICAL ILLNESSES RELATED TO CHOLINERGIC DEFICIENCY; ALZHEIMERS'S DISEASE AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-23 US disclosed
US-4727151-A CLEAVED TO DRUGS IN VIVO BY CHEMICAL OR ENZYMATIC HYDROLYSIS INTERX RESEARCH CORPORATION (US) 1988-02-23 US disclosed
US-4178376-A 6,8-DICHLORO-2-DIBUTYLAMINOMETHYL-2-(3',4'-DICHLOROPHENYL)-4 -QUINOLINEMETHANOL DISSOLVED IN SATURATED OR UNSATURATED FATTY ACID INTERX RESEARCH CORPORATION (US) 1979-12-11 US disclosed
US-4160099-A Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives INTERX RESEARCH CORPORATION 1979-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981942-B2 Crystalline form of benzylbenzene SGLT2 inhibitor SLC5A2, SLC5A1, SLC2A4 ALDH1A1 2754/4885EPHX1 3768/4885CHRM2 4602/4885
US-20200115344-A1 CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR P4HA1, ASPH, PAH ALDH1A1 169/4885EPHX1 1002/4885CHRM2 4684/4885
US-10703751-B2 Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof JAK1, JAK2, JAK3 ALDH1A1 1419/4885EPHX1 3768/4885CHRM2 1181/4885
US-20200239510-A1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR SLC5A2, SLC5A1, SLC2A4 ALDH1A1 2754/4885EPHX1 3768/4885CHRM2 4602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.