Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846117 | 0.81 | GPR84 (0.73) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL27929607 | 0.80 | GPR84 (1.00) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL18036679 | 0.80 | CHRNB2 (0.59) | GPR84HTR2AHTR2CHTR6 | |
| SCHEMBL18036687 | 0.80 | GPR84 (0.67) | GPR84HTR2AHTR6 | |
| SCHEMBL6846106 | 0.78 | HTR2A (0.71) | GPR84HTR2AHTR1AMPO | |
| SCHEMBL24199403 | 0.77 | GPR84 (0.73) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL2123068 | 0.77 | GPR84 (0.73) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL31415125 | 0.77 | HTR2A (0.75) | GPR84HTR2AHTR1AHTR2CMPO | |
| SCHEMBL28836424 | 0.77 | GPR84 (0.58) | GPR84HTR2AHTR1AMPOHTR6 | |
| SCHEMBL28299859 | 0.77 | GPR84 (0.54) | GPR84HTR2AHTR1AMPOHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083588-B1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-9663498-B2 | Aromatic heterocyclic compounds and their application in pharmaceuticals | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-05-30 | — | — | US | disclosed |
| US-20160251339-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251339-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | MAPT, APP, PSEN1 | GPR84 1926/4885HTR2A 461/4885HTR1A 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.