Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917110 | 0.84 | GPR84 (0.54) | GPR84HTR2ATSHRMTNR1AMTNR1B | |
| SCHEMBL27800276 | 0.81 | PKM (0.56) | GPR84TSHRTACR1 | |
| SCHEMBL18036689 | 0.77 | GPR84 (0.67) | GPR84HTR2AHTR1ATDO2HTR6 | |
| SCHEMBL13544370 | 0.76 | MAOB (0.55) | HTR2ATACR1 | |
| SCHEMBL13544214 | 0.76 | MMP2 (0.50) | HTR2ATACR1SLC6A4 | |
| SCHEMBL6846117 | 0.75 | GPR84 (0.73) | GPR84HTR2AHTR1ATSHRTDO2 | |
| SCHEMBL25139912 | 0.75 | GPR84 (0.63) | GPR84HTR2AHTR1ATSHRTDO2 | |
| SCHEMBL12633102 | 0.74 | GPR84 (0.67) | GPR84HTR2AHTR1AHTR6MPO | |
| SCHEMBL28836424 | 0.74 | GPR84 (0.58) | GPR84HTR2AHTR1ATSHRTDO2 | |
| SCHEMBL27794946 | 0.74 | TSHR (0.61) | GPR84HTR2AHTR1ATSHRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725295-B | Aromatic heterocyclic derivatives and its application on drug | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |