Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.73 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | MPO | P05164 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23269531 | 0.85 | GPR84 (0.73) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL2123068 | 0.81 | GPR84 (0.73) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL31415125 | 0.81 | HTR2A (0.75) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL6846117 | 0.81 | GPR84 (0.73) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL30952647 | 0.79 | HTR2A (1.00) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL14663588 | 0.79 | GPR84 (0.69) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL31535627 | 0.79 | HTR2A (0.71) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL743153 | 0.79 | HTR2A (1.00) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL4496642 | 0.79 | HTR2A (0.71) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL7710633 | 0.79 | HTR2A (0.71) | GPR84HTR2AHTR1AMPOTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225480-B2 | Malic enzyme inhibitors | ME1, RNASE1, ME2 | GPR84 3013/4885HTR2A 4876/4885HTR1A 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.