Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804243 | 0.93 | RORC (0.32) | TRPV1HPGDCRBNRORC | |
| SCHEMBL1802939 | 0.90 | TTK (0.33) | HPGDRORC | |
| SCHEMBL1806965 | 0.90 | HPGD (0.33) | TRPV1HPGDCRBNRORC | |
| SCHEMBL1806714 | 0.87 | TRPV1 (0.32) | TRPV1HPGDCRBN | |
| SCHEMBL1806038 | 0.84 | PDK2 (0.36) | RORC | |
| SCHEMBL1802941 | 0.83 | RORC (0.34) | RORC | |
| SCHEMBL1806467 | 0.82 | RXRA (0.37) | TRPV1RORC | |
| SCHEMBL3439106 | 0.82 | EGLN1 (0.33) | — | |
| SCHEMBL1814030 | 0.81 | CCR2 (0.32) | — | |
| SCHEMBL1805629 | 0.81 | TRPV1 (0.33) | TRPV1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | claimed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | claimed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | DDT, LAP3, CYP4X1 | TRPV1 2161/4885HPGD 3741/4885CRBN 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.