Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044610 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL15994560 | 0.96 | — | — | |
| Acetic Acid SCHEMBL28734533 | 0.88 | — | — | |
| SCHEMBL1887392 | 0.85 | HRH4 (0.31) | — | |
| SCHEMBL1398019 | 0.84 | GSK3A (0.32) | — | |
| SCHEMBL31652590 | 0.83 | MAOA (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL13722329 | 0.82 | HRH4 (0.39) | — | |
| SCHEMBL4174560 | 0.82 | HRH1 (0.34) | — | |
| SCHEMBL15228417 | 0.82 | HRH1 (0.34) | — | |
| Water SCHEMBL28158179 | 0.81 | GSK3A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067700-B1 | IMMUNOASSAY FOR PREGABALIN | RANDOX LABORATORIES LTD (GB) | 2022-01-05 | — | — | EP | disclosed |
| US-20160266153-A1 | IMMUNOASSAY FOR PREGABALIN | RANDOX LABORATORIES LIMITED (GB) | 2016-09-15 | — | — | US | disclosed |
| EP-3067700-A1 | IMMUNOASSAY FOR PREGABALIN | Randox Laboratories Ltd. (GB) | 2016-09-14 | — | — | EP | disclosed |