Chamazulene

Chamazulene

SCHEMBL180449

CCc1ccc(C)c2ccc(C)c-2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TRPA1 O75762 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
HTR7 P34969 2/20 0.39
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chamazulene SCHEMBL29562128 1.00 LMNA (0.50) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL27995671 0.82 EGFR (0.39) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL5165125 0.82 CNR1 (0.55) LMNAHTR7LPLLIPGALOX5
SCHEMBL29144243 0.80 ALDH1A1 (0.38) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL29144241 0.80 ALDH1A1 (0.38) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL26968759 0.79 SKP2 (0.56) LMNAALDH1A1SMN1; SMN2NPC1MAPK1
SCHEMBL2185559 0.78 ALDH1A1 (0.41) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL29441542 0.77 TRPA1 (0.48) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL270167 0.77 TRPA1 (0.48) LMNAALDH1A1SMN1; SMN2NPC1MAPT
SCHEMBL26968743 0.77 SKP2 (0.50) LMNAALDH1A1KDM4ELPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651713-A1 PLANT TREATMENT COMPOSITIONS COMPRISING CHITOSAN-COATED EMULSIONS Universität Münster (DE) 2025-11-26 EP claimed
EP-4593977-A1 PRODUCTS AND METHODS RELATED TO THE DISTILLATION OF MOLECULES FROM AEROSOLS Natural Extraction Systems, LLC (US) 2025-08-06 EP claimed
EP-4577181-A1 ORAL CARE COMPOSITIONS Adyani Consulting Corp. (US) 2025-07-02 EP claimed
WO-2025090057-A1 ENCAPSULATION OF INSECTICIDES INTO BIOPOLYMER CAPSULES UNM RAINFOREST INNOVATIONS (US) 2025-05-01 WO claimed
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN claimed
CN-116148388-B Detection method of adulterated Artemisia mongolica in mugwort medicinal materials and decoction pieces 河南省药品医疗器械检验院(河南省疫苗批签中心) 2024-11-01 CN claimed
US-20240293628-A1 SPRAY DEVICE AND AIR TREATMENT DEVICE DAIKIN INDUSTRIES, LTD. (JP) 2024-09-05 US claimed
US-20240269066-A1 USE OF CYP450 INHIBITOR IN INHIBITING OR KILLING MITES AND TREATING XEROPHTHALMIA PRECVISION BIOTECHNOLOGIES LTD. (CN) 2024-08-15 US claimed
EP-4410339-A1 SPRAY DEVICE AND AIR TREATMENT DEVICE Daikin Industries, Ltd. (JP) 2024-08-07 EP claimed
WO-2024153800-A1 PLANT TREATMENT COMPOSITIONS COMPRISING CHITOSAN-COATED EMULSIONS UNIVERSITÄT MÜNSTER (DE) 2024-07-25 WO claimed
CN-1935227-A Medicine composition for improving sleep SSP CO LTD (JP) 2007-03-28 CN claimed
EP-1385505-B1 ACNE TREATMENT WITH LIPOOXIGENASE INHIBITORS ZOUBOULIS CHRISTOS (DE) 2006-07-05 EP claimed
EP-0330240-B1 Camomile drug and its use in the preparation of camomile extracts, camomile oil and pharmaceutical agents ROBUGEN GMBH (DE) 2003-01-15 EP claimed
US-6361806-B1 EMOLLIENTS FOR TOPICAL USE WITH UNSATURATED FATTY ACID AND ANTIINFLAMMATORY AGENT ALLEN MICHAEL P (US) 2002-03-26 US claimed
US-5434122-A Artemesia plant extract ALLOR FOUNDATION (US) 1995-07-18 US claimed
EP-0471668-A1 DEVICE FOR THE TRANSDERMAL DELIVERY OF NICOTINE SCHERING CORPORATION (US) 1992-02-26 EP claimed
WO-1990009808-A1 DEVICE FOR THE TRANSDERMAL DELIVERY OF NICOTINE SCHERING CORPORATION (US) 1990-09-07 WO claimed
EP-0384386-A1 Device for the transdermal delivery of nicotine SCHERING CORPORATION (US) 1990-08-29 EP claimed
US-4908213-A Adhesive polymeric matrix or reservoir delivery patch SCHERING CORPORATION (US) 1990-03-13 US claimed
CN-85108903-A Method for producing a novel anti-inflammatory agent 1986-06-10 CN claimed