Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050286 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL18050351 | 0.96 | ALDH1A1 (0.53) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL18050354 | 0.96 | ALDH1A1 (0.53) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL19875700 | 0.86 | RAB9A (0.55) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL19875699 | 0.86 | RAB9A (0.55) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL2153557 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL18050360 | 0.83 | RAB9A (0.46) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL18050358 | 0.83 | RAB9A (0.46) | SMN1; SMN2RAB9AL3MBTL1HPGDNPC1 | |
| SCHEMBL18069318 | 0.83 | LMNA (0.61) | SMN1; SMN2L3MBTL1ALDH1A1CES2CES1 | |
| SCHEMBL18050253 | 0.83 | LMNA (0.61) | SMN1; SMN2L3MBTL1ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268398-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-05-15 | — | — | EP | disclosed |
| EP-3268398-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142377-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-09-15 | — | — | WO | disclosed |