Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050354 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL18050285 | 0.96 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL18050286 | 0.96 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL19875700 | 0.89 | RAB9A (0.55) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL19875699 | 0.89 | RAB9A (0.55) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL2153557 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL18050360 | 0.86 | RAB9A (0.46) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL18050358 | 0.86 | RAB9A (0.46) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1HPGD | |
| SCHEMBL18050299 | 0.84 | MAPT (0.44) | ALDH1A1SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL18050297 | 0.84 | MAPT (0.44) | ALDH1A1SMN1; SMN2RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268398-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-05-15 | — | — | EP | disclosed |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-04-02 | — | — | US | disclosed |
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-02-22 | — | — | US | disclosed |
| EP-3268398-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142377-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | C1S, CCNT1, COG1 | ALDH1A1 3155/4885SMN1; SMN2 3916/4885RAB9A 2408/4885 |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | C1S, CCNT1, COG1 | ALDH1A1 3155/4885SMN1; SMN2 3916/4885RAB9A 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.