Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 10/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050890 | 0.92 | SCD (0.56) | SCDPKMTSHRGAAADRA1D | |
| SCHEMBL18050879 | 0.84 | NPC1 (0.47) | SCDPKMTSHRGAARAB9A | |
| SCHEMBL20591080 | 0.83 | PKM (0.66) | SCDPKMTSHRGAAS1PR5 | |
| SCHEMBL20591091 | 0.80 | SCD (0.46) | SCDPKMTSHRGAAS1PR5 | |
| SCHEMBL18050897 | 0.80 | PKM (0.49) | SCDPKMTSHRGAARAB9A | |
| SCHEMBL18050874 | 0.80 | SCD (0.49) | SCDPKMTSHRGAARAB9A | |
| SCHEMBL18050896 | 0.79 | PKM (0.46) | SCDPKMTSHRGAAADRA1D | |
| SCHEMBL28432659 | 0.79 | RAB9A (0.43) | RAB9ACCNCCDK8 | |
| SCHEMBL7987743 | 0.78 | SCD (0.50) | SCDPKMTSHRGAAADRA1D | |
| SCHEMBL2145728 | 0.78 | SCD (0.50) | SCDPKMTSHRGAAADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | GUANGZHOU INSIGHTER BIOTECHNOLOGY CO.,LTD. (CN) | 2018-12-27 | — | — | US | disclosed |
| WO-2016141736-A1 | GLYCALPYRAMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF ANTICOCCIDIAL DRUG | 广州英赛特生物技术有限公司 | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | CYP3A5, DDC, CPS1 | SCD 3208/4885PKM 938/4885TSHR 4340/4885 |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | CYP3A5, DDC, CPS1 | SCD 3208/4885PKM 938/4885TSHR 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.